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Search Results for " guanylyl cyclase c "

Targets Recommended: Guanylate cyclase

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T80067	Uroguanylin (human)	Guanylate cyclase	GPCR/G Protein
	Uroguanylin (human) 作为一种在转移性结直肠癌肿瘤中表达的观音酰环化酶(GCC)受体的天然配体，Guanylyl Cyclase 在人类结肠癌动物模型中展现出抗肿瘤活性。
T76334	Cenderitide
	Cenderitide 是一种有效的颗粒鸟酰基环化酶受体 (pGC) 激动剂。Cenderitide 是一种由 C 型利钠肽 (CNP) 与石斛利钠肽 (DNP) 的 C 端融合而成的利钠肽 (NP) 。Cenderitide 可激活 pGC-A 和 pGC-B，激活第二信使 cGMP，抑制醛固酮 (aldosterone)，在不降低血压的情况下保持 GFR 。Cenderitide 可用于心力衰竭的研究。

化合物

Uroguanylin (human)

Cat.No: T80067

Synonym:

Target: Guanylate cyclase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00911	GUCY2C Protein, Human, Recombinant (hFc) GUC2C,STAR,hSTAR,GC-C,ST...	Human	HEK293 Cells
	GUCY2C Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P25092.
TMPJ-00910	GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated Intestinal guanylate cyclase,STAR...	Human	HEK293 Cells
	GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 65-110 KDa and the accession number is P25092.
TMPK-00990	GUCY2C Protein, Mouse, Recombinant (His & Avi) GC-C,STAR,DIAR6,GCC,GU	Mouse	HEK293 Cells
	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1.
TMPK-00856	GUCY2C Protein, Human, Recombinant (His & Avi) GCC,STAR,STA receptor,Guanyly...	Human	HEK293 Cells
	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 48.8 kDa and the accession number is P25092-1.
TMPK-01279	GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) GUC2CEC 4.6.1.2,GCC<...	Cynomolgus	HEK293 Cells
	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.2 kDa and the accession number is XP_005570270.1.
TMPK-01388	GUCY2C Protein, Canine, Recombinant (aa 21-430, His) GC-C,GUCY2C,STAR,EC<...	Canine	HEK293 Cells
	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Canine, Recombinant (aa 21-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.6 kDa and the accession number is F1PAG3.
TMPK-00991	GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated EC 4.6.1,Guanylyl cyc	Mouse	HEK293 Cells
	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1.
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.